Home ProductsSARMS Anabolic Steroids

Hubei Holy Biological Co., Ltd.

Certification
Good quality Raw Steroid Powders for sales
Good quality Raw Steroid Powders for sales
Customer Reviews
I m keeping business with this company from last year, Im always very happy with their product. Thanks agine

—— Robert From US

I got my package. Very fast. First time. No hassles. Thank you for your patience. I will be making some more orders soon

—— Luis From Australia

I have got the parcel and the gift. Thank you for the new year gift Sunny, my wife like it a lot. I will have more order in the new year.

—— Jordan From US

Thank you Sunny. I am feeling better with your hgh. I have lost 4kgs, and all is well. :-) I will keep connect with you for next order.

—— Andrew from US

Have purchase with Jackson he is so faster to contact best quality products ! 100% satisfaction

—— Rafael from Brazil

The shipping is amazing, the products arrived in only 4 days. And the quality is really good. The feedback form our customers are all positive. Thanks

—— Rocky From UK

I am very happy with the stealthy package, and especially the shipping this time was very fast. I look forward to working with you again.

—— Toufik From France

I have cooperated with Sunny many times. She is very kind all the time. All the products I bought from her are good. She is our regular supplier now.

—— Aaron From Canada

Very happy to do business with your guys. I have tried it :-) Good result. Hope we can do more deals in future.

—— Dasith From Russia

Thanks for your sample gift, really like it, we could add it in next order.

—— Ashley From US

Hi Sunni yes I am very happy with the parcel can you give me a price for ten kits of growth hormone (jintropin) and ten bottles of blue top melanotan?

—— Chris

Just make a test, it is veeeeery niceeee! The best quality

—— Luis From Brazil

I'm Online Chat Now

High 99% Purity Sarms Aicar Acadesine Powder For Muscle Mass CAS 2627-69-2

China High 99% Purity Sarms Aicar Acadesine Powder For Muscle Mass CAS 2627-69-2 supplier
High 99% Purity Sarms Aicar Acadesine Powder For Muscle Mass CAS 2627-69-2 supplier High 99% Purity Sarms Aicar Acadesine Powder For Muscle Mass CAS 2627-69-2 supplier High 99% Purity Sarms Aicar Acadesine Powder For Muscle Mass CAS 2627-69-2 supplier

Large Image :  High 99% Purity Sarms Aicar Acadesine Powder For Muscle Mass CAS 2627-69-2

Product Details:

Place of Origin: China
Brand Name: Holybiological
Certification: ISO9001, SGS
Model Number: 2627-69-2

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Price: Negotiation
Packaging Details: Foil bag
Delivery Time: Within 24 hours
Payment Terms: Western Union, MoneyGram, T/T, Bitcoin
Supply Ability: 300kg/month
Contact Now
Detailed Product Description
Purity: 99% Shipment: FedEx, EMS, HKEMS, TNT, DHL, UPS
Policy: Re-Shipping Policy WhatsApp: +8613545014917

High 99% Purity Sarms Aicar Acadesine Powder For Muscle Mass CAS 2627-69-2

 

Product Details

Other name: Acadesine,AICAR,AICA-RIBOSIDE,AMPK,Z-RIBOSIDE
CAS: 2627-69-2
EINECS: 220-097-5
Molecular Formula: C9H14N4O5
Molecular Weight: 258.23
Assay: 99%
Apperance: White or off-white powder.
Usage: Pharmaceutical intermediates. For the treatment of cardiovascular diseases

 

Aicar is a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with Aicar mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle.

 

High 99% Purity Sarms Aicar Acadesine Powder For Muscle Mass CAS 2627-69-2

 

Function

AICAR strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes. Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK, and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase). The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.

AMP-activated protein kinase (AMPK) functions as a metabolic sensor that regulates lipid and glucose metabolism to maintain cellular energy homeostasis and to protect against metabolic stress.AICAR is a selective activator of AMPK in both hepatocytes and adipocytes. At 0.5 mM it inhibits the synthesis of fatty acids and sterols and inactivates HMG-CoA reductase in rat hepatocytes.AICAR (0.5 mM) inhibits insulin-stimulated glucose uptake to 62% of controls and reduces GLUT4 translocation 2.5-fold in 3T3-L1 adipocytes. It also blocks the expression of pro-inflammatory cytokines (TNF-α/IL-1β and IL-6), iNOS, COX-2, and MnSOD genes in glial cells and macrophages by inhibiting NFκB and C/EBP pathways.

 

COA

Item
Specification

Result

Appearance


White powder

Complies

Related substance (HPLC)

Total impurity ≤0.5%
Max single impurity ≤0.1%

0.2%
0.06%

Odor

Characteristic

Complies

Assay

99%

99.8%

Sieve analysis

100% pass 80 mesh

Complies

Loss on Drying
Residue on Ignition

≤1.0%
≤1.0%

0.12%
0.09%

Heavy Metal

<10ppm

Complies

As

<0.1ppm

0.05ppm

Pb

<0.1ppm

0.05ppm

Cd

<0.1ppm

0.05ppm

Residual Solvents

<100ppm

Complies

Residual Pesticide

Negative

Complies

Microbiology
   

Total Plate Count

<1000cfu/g

Complies

Yeast & Mold

<100cfu/g

Complies

E.Coli

Negative

Complies

Salmonella

Negative

Complies

 

High 99% Purity Sarms Aicar Acadesine Powder For Muscle Mass CAS 2627-69-2

 

Application
Aicar (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR& alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes.
Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase).
The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.

 

SARMS Product List

YK11 431579-34-9
AICAR 2627-69-2
Ostarine(mk-2866,enobosarm) 841205-47-8,1202044-20-9
Andarine(S4) 401900-40-0
Andarine(GTX-007) 401900-40-1
Mk-677(Ibutamoren) 159752-10-0
LGD-4033 1165910-22-4
GW-501516(cardarine) 317318-70-0
SR9009 137986-29-9
RAD-140 118237-47-0

 

 

 

Contact Details
Hubei Holy Biological Co., Ltd.

Contact Person: Mr. Jackson

Send your inquiry directly to us (0 / 3000)